Acacia concinna herb Shikakai pods use in medicine
February 1 2017

Benefits and review
The beneficial substances in Acacia concinna are extracted from the pods of the shrub. Acacia Concinna grows in abundance in the hot, dry climates of Central Asia and the Far East. The pods of this plant are rich in saponins which are foam forming substances. Acacia concinna is known in Ayurvedic medicine as Shikakai.

Fibrosarcoma
J Nat Prod. 2000. Kinmoonosides A-C, three new cytotoxic saponins from the fruits of Acacia concinna, a medicinal plant collected in myanmar. Kinmoonosides A-C showed significant cytotoxicity against human HT-1080 fibrosarcoma cells.

Acacia concinna for hair
The fruit pods, leaves and bark of Acacia Concinna are dried, powdered and made into a paste at home. While this paste does not produce the normal amount of lather that a regular shampoo would, it is a good cleanser.

Vaccine and immune system
Immunological adjuvant activities of saponin extracts from the pods of Acacia concinna.
Int Immunopharmacol. 2006. Kukhetpitakwong R, Hahnvajanawong C, Homchampa P, Leelavatcharamas V, Satra J, Khunkitti W. Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Pods of Acacia concinna contain several saponins. In this study, four saponin fractions which were acetone fraction, aqueous fraction, hydromethanolic fraction and methanolic fraction (MAC) were generated and their haemolytic activities and surface activities were determined in comparison with quillaja saponin. In conclusion, the results indicated that MAC at a dose of 40 microg could be used as vaccine adjuvant to increase immune responses.

Constituents and chemicals, substances
Pods of Acacia concinna contain several saponins including kinmoonosides A-C, triterpenoidal prosapogenols named concinnosides A, B, C, D, and E, together with four glycosides, acaciaside, julibroside A1, julibroside A3, albiziasaponin C, and their aglycone, acacic acid lactone. Their interaction with 5htp dietary supplement along with their benefit side effects and dosage need further exploration.