Anthocyanidin health benefit and antioxidant benefit, medical uses
February 1 2017

Anthocyanidins are anthocyanins that are not attached to a sugar molecule. Anthocyanins are water-soluble flavonoid pigments that appear red to blue. They are synthesized by organisms of the plant kingdom, and have been observed to occur in all tissues of higher plants, providing color in leaves, stems, roots, flowers, and fruits. Scientists have identified hundreds of different anthocyanidins, including pelargonidin, malvidin, delphinidin, peonidin, and cyanidin.

Health benefit
Major sources of anthocyanidins in the American diet are bilberries, blueberries, cherries, raspberries, strawberries, black currants, purple grapes and red wine. Anthocyanidins have a wide range of biological activities including antioxidant, anti-inflammatory, antimicrobial and anti-cancer activities. In addition they display a variety of effects on blood vessels, platelets and lipoproteins able to reduce the risk of coronary heart diseases. You can improve your health by including a wide range of berries in your diet.

It has been reported that anthocyanidins decrease hepatic lipid accumulation and may counteract oxidative stress and hepatic inflammation.

Delphinidin anthocyanidin
Delphinidin, a major biologically active anthocyanidin found in berries, inhibits the vascular endothelial growth factor (VEGF)-induced phosphorylation and blocks angiogenesis in vitro and in vivo.

Anthocyanins and anthocyanidins information
Anthocyanins, which are O-glycosylated derivatives of anthocyanidins, are responsible for the red, blue and purple coloration of many organs of angiosperms. See also information about a related group of compounds known as proanthocyanidins.

Pain relief?
An examination of anthocyanins’ and anthocyanidins’ affinity for cannabinoid receptors.
A growing body of evidence suggests that anthocyanins and anthocyanidins may possess analgesic properties in addition to neuroprotective and anti-inflammatory activities. These functionalities suggest a role for the cannabinoid receptor in mediating biological effects. Cyanidin and delphinidin as ligands with moderate affinity to human CB1. For CB2, similar affinities were achieved by cyanidin, delphinidin, and peonidin. Inhibition constants were obtained for pelargonidin, malvidin, cyanidin-3,5-di-O-glucoside, cyanidin-3-O-glucoside, cyanidin-3-O-galactoside, and cyanidin-3-O-rutinoside for both CB subtypes. J Med Food. 2009; Korte G, Dreiseitel A, Schreier P, Oehme A, Locher S, Hajak G. Department of Psychiatry, University of Regensburg, Regensburg, Germany.

You can purchase Bilberry extract as a supplement and get a healthy amount of anthocyanidins

Bilberry Supplement Facts:
Serving Size: 1 bilberry capsule
Bilberry Fruit Standardized Extract – 80 mg
(Vaccinium myrtillus)
Yielding 20 mg anthocyanosides, anthocyanidins


Bilberry extract contains anthocyanosides, anthocyanins, anthocyanidins, and proanthocyanidins. Bilberry extract, also referred to as blueberry, is a potent extract yielding key bioflavonoids called anthocyanosides or anthocyanins. A controlled extraction process guarantees at least 25% anthocyanosides. 5-htp pills or tablets can be taken with bilberry or blueberry extracts.